RESUMO
Challenges of the extrauterine environment can be life threatening for a premature fetus with inadequate fetal maturity. Maternal corticosteroids therapy is widely employed to induce fetal pulmonary maturation. Nevertheless, whenever therapeutic pregnancy interruption has to be performed in a time manner insufficient to treat the dam, postnatal corticotherapy can be considered an alternative. However, it is not known if antenatal and postnatal corticotherapy can improve similarly neonatal outcomes and pulmonary function. This research aimed to analyze antenatal and postnatal corticotherapy on premature lambs vitality, pulmonary functioning, metabolic and oxidative status. Lambs were evaluated according to the mode of treatment: Prenatal Corticosteroid Group (8 lambs born after maternal betamethasone treatment 48 h prior to birth), Postnatal Corticosteroid Group (9 lambs subjected to betamethasone treatment 10 min after birth) and Control Group (5 lambs remained untreated). Lambs were medically followed-up from birth to 72 h thereafter through a complete physical examination, as well as lactatemia, glycaemia, blood acid-base balance and antioxidant status. Treated lambs had higher vitality score than the Control Group. Heart rate was higher in postnatal therapy compared to prenatal treatment. Respiratory rate and rectal temperature were higher in treated groups. Treated lambs had hyperglycemia, while the Postnatal Group had higher lactatemia than the Control Group. The Prenatal Group had lower and normal pCO2 from 60 min onwards. The Postnatal Group had higher superoxide dismutase activity than untreated lambs. In conclusion, prenatal and postnatal betamethasone treatments favor neonatal clinical outcome, respiratory function, glucose homeostasis and oxidative balance.
Assuntos
Betametasona , Taxa Respiratória , Corticosteroides/metabolismo , Animais , Feminino , Glucocorticoides/farmacologia , Pulmão , Estresse Oxidativo , Gravidez , OvinosRESUMO
Se realizó un estudio prospectivo y longitudinal de 42 adultos, de ambos sexos, con cardiopatía isquémica, tratados con cirugía correctora sin circulación extracorpórea en el Centro Territorial de Cirugía Cardiovascular de Santiago de Cuba, con vistas a medir la masa libre de grasa mediante el método de bioimpedancia eléctrica, durante el primer cuatrimestre del 2014. Los resultados mostraron que el promedio de masa libre de grasa en el periodo posoperatorio fue significativamente mayor (p<0,05) que el de la medición en el periodo preoperatorio. Se concluyó que este aumento fue interpretado como una sobrestimación presumiblemente causada por factores orgánicos que afectaron la técnica de medición(AU)
A prospective and longitudinal study of 42 adults, of both sexes, with ischemic heart disease, treated with corrective surgery without heart-lung machine was carried out in the Territorial Center of Cardiovascular Surgery in Santiago de Cuba, aimed at measuring the fat free mass by means of the method of electric bioimpedancy, during the first quarter of 2014. The results showed that the fat free mass average of the postoperative period was significantly higher (p<0,05) than that of the measuring in the preoperative period. It was concluded that this increase was interpreted presumably as an overestimation caused by organic factors that affected the measuring technique(AU)
Assuntos
Humanos , Masculino , Feminino , Adulto , Isquemia Miocárdica/cirurgia , Composição Corporal , Impedância Elétrica , Circulação Extracorpórea , Estudos Transversais , Estudos ProspectivosRESUMO
Se realizó un estudio prospectivo y longitudinal de 42 adultos, de ambos sexos, con cardiopatía isquémica, tratados con cirugía correctora sin circulación extracorpórea en el Centro Territorial de Cirugía Cardiovascular de Santiago de Cuba, con vistas a medir la masa libre de grasa mediante el método de bioimpedancia eléctrica, durante el primer cuatrimestre del 2014. Los resultados mostraron que el promedio de masa libre de grasa en el periodo posoperatorio fue significativamente mayor (p<0,05) que el de la medición en el periodo preoperatorio. Se concluyó que este aumento fue interpretado como una sobrestimación presumiblemente causada por factores orgánicos que afectaron la técnica de medición.
A prospective and longitudinal study of 42 adults, of both sexes, with ischemic heart disease, treated with corrective surgery without heart-lung machine was carried out in the Territorial Center of Cardiovascular Surgery in Santiago de Cuba, aimed at measuring the fat free mass by means of the method of electric bioimpedancy, during the first quarter of 2014. The results showed that the fat free mass average of the postoperative period was significantly higher (p<0,05) than that of the measuring in the preoperative period. It was concluded that this increase was interpreted presumably as an overestimation caused by organic factors that affected the measuring technique.
Assuntos
Composição Corporal , Avaliação Nutricional , Impedância Elétrica , Cirurgia GeralRESUMO
Este texto foi originalmente apresentado na Jornada do Circulo Psicanalitico de 1998 cujo tema foi o desamparo. E um resultado ainda incipiente, inicial, do trabalho realizado no curso que coordeno as sexta-feiras sobre as questoes psicanaliticas clinicas e teoricas evidenciadas pela 'psicossomatica' da primeira infancia. O objetivo final e propor novas possibilidades clinicas diante de um paciente nao convencional, eminentemente contemporaneo, cuja questao central parece estar em sua propria constituicao como sujeito. Partimos dos transtornos 'funcionais' da primeira infancia, por situarem-se neste limite entre corpo e alma, onde se constroem as cisoes fundamentais, para pensarmos sobre a construcao do sujeito, tentando positivar conceitualmente esta area de aparente indefinicoes e imprecisoes para o campo psicanalitico.
